Pfizer plans to drastically ramp up its vaccine production capacity and is prepared to drop German firm that it partnered with on breakthrough Covid jabs
- Pharmaceutical giant plans to use gene-based tech harnessed by BioNTech
- Pfizer said it no longer ‘needs’ BioNTech after their collaboration on Covid jab
- Firm has recruited 50 mRNA scientists to start trials at laboratory in New York
Pfizer has admitted it may ditch the German biotech firm that made its breakthrough coronavirus jab as it looks to drastically expand its vaccine business.
The US drugs giant has revealed plans to use gene-based technology, harnessed by BioNTech, to tackle other viruses and illnesses beyond Covid.
Pfizer’s boss claimed it had learned everything it needs to about mRNA vaccines to go solo, adding that it no longer ‘needs to work with BioNTech’ beyond the end of the companies’ Covid jab agreement in July.
Albert Bourla, the firm’s chief executive, revealed the company had recruited at least 50 more scientists to work out of its new mRNA-focused lab in New York.
It has also secured specialised raw materials and designed clinical trials so that it can manufacture and study vaccines without splitting profits.
Mr Bourla told the Wall Street Journal: ‘We like working with BioNTech, but we don’t need to work with BioNTech. We have our own expertise developed.’
The German company was the brains behind the Covid jab, which was proven to be 95 per cent effective at blocking Covid symptoms and became the first in the world to get approval in December when Britain gave it the green light.
Pfizer, most famous for inventing Viagra, came on board to manufacture, distribute and commercialise the vaccine.
The two companies are currently splitting profits on the Covid jab evenly, with sales expected to return roughly £13billion this year.
Albert Bourla, Pfizer’s chief executive, said the drugs giant no longer ‘needs to work with BioNTech’
The German firm was the brains behind the Covid jab — proven to be 95 per cent effective — which was the first in the world to get approval in December in Britain (file)
Analysts at JP Morgan forecast more than £8.5bn in sales for the jab next year, which will increase if annual booster shots are needed.
A BioNTech spokeswoman told the WSJ: ‘We consider it a great acknowledgment for mRNA technologies that companies such as our partner Pfizer are getting involved into building their own mRNA vaccine strategy.’
The two firms first began to collaborate in 2018 with the aim of making a flu vaccine.
But that original deal expires this July, at which point Pfizer will continue to research, manufacture and sell any jab proven to work.
How do mRNA vaccines work?
MRNA is a next generation technology, or platform, to use vaccine terminology.
Traditional vaccines use one harmless, typically inactivated virus – such as the types that cause common colds – to deliver a tiny, harmless piece of the virus that the shot will provide protection against to the human body.
The piece is enough to ‘teach’ the immune system how to recognize and fend off the invader.
MRNA is easier and faster to make, and much more easily modified than older types of vaccines, and even has the potential to provide protection against multiple viruses in one vaccine.
The coronavirus vaccine is made from volatile genetic material known as mRNA, or messenger RNA, tiny pieces of genetic material that mimic the coronavirus so the immune system can learn to spot and destroy it.
Scientists say mRNA vaccines are cheaper to make and easier to modify in the face of new variants or viruses.
The process of developing mRNA vaccines is also purely synthetic, meaning experts don’t have to rely on living cells from plants or animals.
Making mRNA vaccines requires special equipment and raw materials that weren’t commonly available before Covid hit.
Pfizer/BioNTech’s Covid jab was the first ever mRNA vaccine to get approval for fighting any disease. Rival American firm Moderna has also created an mRNA jab proven to thwart coronavirus.
Pfizer’s boss said it has become self-sufficient after learning how to produce mRNA vaccines itself, without relying on suppliers.
The New York-based firm, which is one of the world’s biggest pharmaceuticals, has declined to say which viruses it will target next with the mRNA technology.
But it’s likely booster coronavirus shots will be needed in the future as new variants emerge. The global flu vaccination market is also valued at about £3bn.
Pfizer’s vaccine portfolio already includes one of the most profitable jabs on the market — the pneumonia vaccine Prevnar 13. It made Pfizer nearly £4.3bn in sales last year.
It is also using traditional vaccine technology to develop shots for Lyme disease and colon infections.
Traditional vaccines use one harmless, typically inactivated virus – such as the types that cause common colds – to teach the immune system to recognise the threat and kill it in future.
Moderna jabs will be rolled-out in 3 weeks to the under-50s as Britain’s vaccine drive shifts up a gear
Britain’s world-beating vaccine rollout will move up another gear in mid-April when the Moderna jab is deployed for the first time, The Mail on Sunday understands.
The imminent arrival of more than 500,000 doses of the new US vaccine – to add to millions of Pfizer and Oxford-AstraZeneca shots – will herald the expansion of the programme to the under-50s.
Doctors are expected to administer the first Moderna jabs within three weeks.
Moderna, which was codenamed ‘Renown’ by the Government during the American company’s development process, is being manufactured by the Swiss-based Lonza biotech company.
Trials found that it was 94.1 per cent effective at preventing symptomatic infection after the second dose.
More than 30 million vaccine first doses have now been administered in the UK.