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At least 20 people were receiving treatment for the disease as of October 8, according to Primary Health Care.
The Athabasca Health Authority (AHA) has now declared a tuberculosis outbreak.
Cases of the bacterial outbreak were reported in the Black Lake and Fond Du Lac communities.
As of Tuesday, nine people were being treated in Fond du Lac, according to Executive Director of Primary Health, Taiwo Olubanwo.
Officials have also reported 70 close contacts.
Six people were also being treated in Black Lake, with 157 close contacts identified.
About 90.5 percent are considered a high risk of transmission.
Tuberculosis is a respiratory disease that is spread through bacterial infections.
According to Mr Olubanwo, all patients range in age from just five weeks to 63-years-old.
Overcrowded households may have contributed to the disease’s outbreak.
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