Emergency services were called shortly after 9.30pm on Wednesday night following reports of an injured man on Moorland Road in Lambeth. The Met Police said officers found a man in his mid-20s suffering from what are believed to be gunshot injuries and stab wounds.
He was taken by the London Ambulance Service (LAS) to a nearby hospital.
Police said his condition is not life-threatening but may be life-changing.
A 17-year-old male has been arrested on suspicion of attempted murder and remains in police custody.
Crews from the Met Police’s firearms unit and an air ambulance also attended the scene.
Met Police officers at the scene were targeted by a group of people throwing objects, Scotland Yard said this morning.
Specialist support officers were deployed and attempted to work with and disperse the gathering.
The force confirmed no officers on duty are believed to have sustained any serious injuries during the incident.
A police cordon remains in place this morning and officers are on duty to support local residents.
Anyone with information is urged to contact the police via 101 quoting reference Cad 7951/02Jun.
In a statement, the Met Police said: “An investigation is ongoing following a serious incident in Lambeth last night.
“Police were called by the London Ambulance Service at 21:37hrs on Wednesday, 2 June to reports of an injured man on Moorland Road, SW9.
“Officers, including firearms officers, and London’s Air Ambulance attended.
“A man, aged in his mid-20s, was found suffering what are believed to be gunshot injuries and stab wounds.
“He was taken by the LAS to a south London hospital; his condition has been assessed as not life-threatening but may be life-changing.
“A 17-year-old male has been arrested on suspicion of attempted murder and remains in police custody.
“Whilst at the scene, officers were approached by a large group of people and objects were thrown towards them.
“Officers from the Territorial Support Group attempted and worked to disperse the crowds.”
The force added: “A crime scene is in place and a police presence remains in the area for the reassurance of local residents.”